Behind the claims of supplements
Several supplements fall into this group.
Chromium: Chromium in dietary supplements is usually in the form of chromium piccolinate. Chromium is an essential mineral that plays a role in carbohydrate and lipid metabolism, but its role as a weight-loss aid is less clear. A formal analysis of 10 randomized studies found that chromium achieved small weight losses of about 2½ pounds over 6 to 14 weeks.
Conjugated linoleic acid, or CLA: These trans-fatty acids are supposed to interfere with fat deposition. Mouse studies suggested some benefit in obese mice; however, trials in humans produced no change in body mass index. CLA is found naturally in dairy foods and beef, and so is generally considered safe. Side effects included mild to moderate gastrointestinal complaints.
Garcinia cambogia: This is a tropical fruit native to India from which hydroxycitric acid, or HCA, is derived. HCA may inhibit fatty acid synthesis. Results of trials using this supplement have been mixed, however. In one 12-week study, women who took HCA lost an average of 3 pounds more than those who didn’t. In another, larger study, HCA had no apparent effect.
Pyruvate: Pyruvate is produced in the body naturally through the breakdown of carbohydrates and protein. It is claimed to increase metabolism and reduce body fat. Some studies have suggested that pyruvate may improve body composition and enhance exercise performance.
